Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02584
Species: Mus musculus
Position : chr10:87376120-87376374
Year: 2021
Title: The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  34739481
MONDO:
Tissue: Central nervous system
Tissue Ontology ID: UBERON:0001017
Cell Source: Embryonic neuroprogenitor cells
CVCL ID:
Cell Type: neural progenitor cell
Cell Ontology ID: CL:0002672
Experiment Type: Functional perturbation assay, Enhancer activity assay
High Throughput Method:
Low Throughput Method: CRISPR Knockout, qRT-PCR, In situ hybridization, Immunohistochemistry
About Target Gene
Target gene : Nes
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer