Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02608
Species: Mus musculus
Position : chr3:34756748-34761748
Year: 2023
Title: FACT regulates pluripotency through proximal and distal regulation of gene expression in murine embryonic stem cells
Genome Build: mm10
Enhancer Type: Super-enhancer
Condition: Normal
Disease Name: --
PMID:  37542287
MONDO:
Tissue: Embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: murine embryonic stem cells (mESCs)
CVCL ID:
Cell Type: mouse embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, qRT-PCR
About Target Gene
Target gene : Sox2
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 6 found
Enhancer ID Position Tissue Cell Disease
E_02892 chr3:34752523-34766449 Embryo mouse embryonic stem cell --
E_02893 chr3:34752523-34766449 Embryo mouse embryonic stem cell --
E_03381 chr3:34757100-34758037 Embryo mouse embryonic stem cell --
E_03382 chr3:34757100-34758037 Embryoid body pluripotent stem cell --
E_03383 chr3:34761100-34762000 Embryo mouse embryonic stem cell --
E_03384 chr3:34761100-34762000 Embryoid body pluripotent stem cell --
Expression of Target Genes for the Enhancer