Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02617
Species: Homo sapiens
Position : chr15:38846389-38846967
Year: 2019
Title: Mechanistic Characterization of RASGRP1 Variants Identifies an hnRNP-K-Regulated Transcriptional Enhancer Contributing to SLE Susceptibility.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  31164884
Tissue: kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: HEK293
CVCL ID: CVCL_0045
Cell Type: embryonic kidney cell
Experiment Type: Enhancer activity assay
High Throughput Method: ChIP-seq; RNA-seq; eQTL analysis
Low Throughput Method: Luciferase Reporter Assay; EMSA; ChIP-RT-qPCR; Reporter assay; ChIP-qPCR; qPCR
About Target Gene
Target gene : RASGRP1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_02604 chr15:38845678-38847678 blood T cell systemic lupus erythematosus
E_02605 chr15:38846389-38846967 blood T lymphoblast T-cell acute lymphoblastic leukemia
Expression of Target Genes for the Enhancer