Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02621
Species: Homo sapiens
Position : chr2:11623044-11625344
Year: 2026
Title: MYC-bound enhancer RNAs in cis regulate gene transcription and tumorigenesis.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Disease
Disease Name: breast cancer
PMID:  42030388
MONDO: MONDO:0007254
Tissue: mammary gland
Tissue Ontology ID: UBERON:0001911
Cell Source: BT-474
CVCL ID: CVCL_0179
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Enhancer functional assay; chromatin remodeling assay
High Throughput Method: ChIP-qPCR
Low Throughput Method: ASO-mediated MERG1 knockdown; qRT-PCR; Western blot
About Target Gene
Target gene : GREB1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 1 found
Enhancer ID Position Tissue Cell Disease
E_02465 chr2:11623044-11625344 mammary gland malignant cell breast cancer
Expression of Target Genes for the Enhancer