About Enhancer
| Enhancer ID: | E_02626 |
| Species: | Danio rerio |
| Position : | chr2:38181326-38182075   |
| Year: | 2023 |
| Title: | An injury-responsive mmp14b enhancer is required for heart regeneration. |
| Genome Build: | danRer11 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 38019918 |
| Tissue: | heart |
| Tissue Ontology ID: | UBERON:0000948 |
| Cell Source: | injured adult zebrafish cardiac endothelial cells |
| Cell Type: | cardiac endothelial cell |
| Cell Ontology ID: | CL:0010008 |
| Experiment Type: | Enhancer activity assay; TF-motif binding assay; Endogenous functional perturbation assay |
| High Throughput Method: | ATAC-seq; RNA-seq |
| Low Throughput Method: | Tol2 transgenic reporter assay; enhancer deletion scanning; TEAD-site mutagenesis; EMSA with recombinant TEAD3; CRISPR/Cas9 endogenous enhancer deletion; RT-qPCR; RNA in situ hybridization |
About Target Gene
| Target gene : | mmp14b |
About TF
| TF name : | tead3a |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (danRer11)
No overlapping enhancers found in danRer11 at this locus.
Expression of Target Genes for the Enhancer