About Enhancer
| Enhancer ID: | E_02642 |
| Species: | Mus musculus |
| Position : | chr8:125454150-125454370   |
| Year: | 2015 |
| Title: | Enhancer cooperativity as a novel mechanism underlying the transcriptional regulation of E-cadherin during mesenchymal to epithelial transition |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 25652130 |
| MONDO: | |
| Tissue: | Mammary gland |
| Tissue Ontology ID: | UBERON:0001911 |
| Cell Source: | NMuMG cells |
| CVCL ID: | CVCL_0077 |
| Cell Type: | mammary epithelial cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | TF binding assay |
| High Throughput Method: | |
| Low Throughput Method: | ChIP-RT-qPCR |
About Target Gene
| Target gene : | Cdh1 |
About TF
| TF name : | Hnf4A |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Hnf4A | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| Hnf4A | HIF-1-alpha transcription factor network | pid | 67 |
| Hnf4A | Nuclear Receptor transcription pathway | reactome | 51 |
| Hnf4A | Regulation of gene expression in beta cells | reactome | 17 |
| Hnf4A | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Hnf4A | TGF_beta_Receptor | netpath | 220 |
| Hnf4A | Maturity onset diabetes of the young | kegg | 25 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer