About Enhancer
| Enhancer ID: | E_02643 |
| Species: | Homo sapiens |
| Position : | chr12:68551520-68552520   |
| Year: | 2009 |
| Title: | Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 19458616 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | CCR5+ Th1 effector memory CD4+ T cells |
| Cell Type: | T-helper 1 cell |
| Cell Ontology ID: | CL:0000545 |
| Experiment Type: | Chromatin interaction assay; TF binding assay; Functional perturbation assay |
| Low Throughput Method: | CTCF/RAD21 ChIP-qPCR; 3C; 3D-FISH; siRNA knockdown; RT-qPCR |
About Target Gene
| Target gene : | IFNG |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer