Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02666
Species: Homo sapiens
Position : chr6:31126537-31126685
Year: 2016
Title: A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  26813977
Cell Source: Embryonic Stem Cell
Experiment Type: Enhancer activity assay; Chromatin interaction assay; Endogenous enhancer perturbation; In vivo functional validation
High Throughput Method: 4C-seq
Low Throughput Method: Luciferase reporter assay; Reporter assay; CRISPR-Cas9 targeted editing/deletion
About Target Gene
Target gene : POU5F1
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_02657 chr6:31126537-31126685 embryo embryonic stem cell NA
E_02662 chr6:31126537-31126685 embryonic stem-cell culture embryonic stem cell NA
Expression of Target Genes for the Enhancer