About Enhancer
| Enhancer ID: | E_02675 |
| Species: | Homo sapiens |
| Position : | chr6:30904342-30904788   |
| Year: | 2016 |
| Title: | A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26813977 |
| Tissue: | inner cell mass |
| Tissue Ontology ID: | UBERON:0000087 |
| Cell Source: | WA01 |
| CVCL ID: | CVCL_9771 |
| Cell Type: | embryonic stem cell |
| Cell Ontology ID: | CL:0002322 |
| Experiment Type: | Functional perturbation assay, Genetic screen; Endogenous enhancer perturbation |
| High Throughput Method: | ChIP-seq; CRISPR genetic screen |
| Low Throughput Method: | CRISPR Knockout; CRISPR-Cas9 endogenous deletion/editing |
About Target Gene
| Target gene : | POU5F1 |
About TF
| TF name : | TEAD4 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| TEAD4 | PPARA activates gene expression | reactome | 113 |
| TEAD4 | YAP1- and WWTR1 (TAZ)-stimulated gene expression | reactome | 29 |
| TEAD4 | Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 | wikipathways | 153 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02664 | chr6:30904342-30904788 | NA | NA | NA |
Expression of Target Genes for the Enhancer