About Enhancer
| Enhancer ID: | E_02676 |
| Species: | Homo sapiens |
| Position : | chr6:31234516-31234664   |
| Year: | 2016 |
| Title: | A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26813977 |
| Tissue: | inner cell mass |
| Tissue Ontology ID: | UBERON:0000087 |
| Cell Source: | WA01 |
| CVCL ID: | CVCL_9771 |
| Cell Type: | embryonic stem cell |
| Cell Ontology ID: | CL:0002322 |
| Experiment Type: | Functional perturbation assay, Genetic screen; Endogenous enhancer perturbation |
| High Throughput Method: | ChIP-seq; CRISPR genetic screen |
| Low Throughput Method: | CRISPR Knockout; CRISPR-Cas9 endogenous deletion/editing |
About Target Gene
| Target gene : | POU5F1 |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer