About Enhancer
| Enhancer ID: | E_02750 |
| Species: | Homo sapiens |
| Position : | chr10:51546800-51547317   |
| Year: | 2016 |
| Title: | Chromatin interactions and candidate genes at ten prostate cancer risk loci. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | cervical cancer |
| PMID: | 26979803 |
| MONDO: | MONDO:0002974 |
| Tissue: | uterine cervix |
| Tissue Ontology ID: | UBERON:0000002 |
| Cell Source: | HeLa |
| CVCL ID: | CVCL_0030 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, TF binding assay |
| High Throughput Method: | Capture 3C-seq; ChIP-seq; RNA-seq; SNP genotyping array; 3C; eQTL analysis |
| Low Throughput Method: | Luciferase reporter assay; Site-directed mutagenesis, 3C-qPCR; RT-qPCR |
About Target Gene
| Target gene : | AGAP7P |
About TF
| TF name : | HOXB13 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| HOXB13 | Regulation of Androgen receptor activity | pid | 54 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
15 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02744 | chr10:51546800-51547317 | uterine cervix | malignant cell | cervical cancer |
| E_02745 | chr10:51546800-51547317 | prostate gland | malignant cell | prostate cancer |
| E_02746 | chr10:51546800-51547317 | uterine cervix | malignant cell | cervical cancer |
| E_02747 | chr10:51546800-51547317 | prostate gland | malignant cell | prostate cancer |
| E_02748 | chr10:51546800-51547317 | uterine cervix | malignant cell | cervical cancer |
| E_02749 | chr10:51546800-51547317 | prostate gland | malignant cell | prostate cancer |
| E_02751 | chr10:51546800-51547317 | prostate gland | malignant cell | prostate cancer |
| E_02800 | chr10:51546800-51547317 | prostate gland | NA | prostate cancer |
| E_02801 | chr10:51546800-51547317 | prostate gland | NA | prostate cancer |
| E_02802 | chr10:51546800-51547317 | prostate gland | NA | prostate cancer |
| E_02803 | chr10:51546800-51547317 | prostate gland | NA | prostate cancer |
| E_02821 | chr10:51546800-51547317 | prostate gland | NA | NA |
| E_02822 | chr10:51546800-51547317 | prostate gland | NA | NA |
| E_02823 | chr10:51546800-51547317 | prostate gland | NA | NA |
| E_02824 | chr10:51546800-51547317 | prostate gland | NA | NA |
Expression of Target Genes for the Enhancer