Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02754
Species: Homo sapiens
Position : chr6:35505138-35511492
Year: 2010
Title: Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions.
Genome Build: hg19
Enhancer Type: Enhancer
Condition: Normal
PMID:  20093418
Tissue: lung
Tissue Ontology ID: UBERON:0002048
Cell Source: A549
CVCL ID: CVCL_0023
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Enhancer activity assay; TF-binding/chromatin assay; In vivo functional validation
Low Throughput Method: Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; RT-qPCR/qPCR
About Target Gene
Target gene : FKBP5
About TF
TF name : CTCF
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
CTCF Activation of anterior HOX genes in hindbrain development during early embryogenesis reactome 120
CTCF TGF_beta_Receptor netpath 220
Enhancer Associated Network
Overlapping Enhancers (hg19) 2 found
Enhancer ID Position Tissue Cell Disease
E_02755 chr6:35505138-35511492 lung malignant cell NA
E_02807 chr6:35505138-35511492 lung malignant cell NA
Expression of Target Genes for the Enhancer