About Enhancer
| Enhancer ID: | E_02837 |
| Species: | Homo sapiens |
| Position : | chr1:204518514-204561889   |
| Year: | 2016 |
| Title: | Chromatin interactions and candidate genes at ten prostate cancer risk loci. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 26979803 |
| MONDO: | MONDO:0008315 |
| Tissue: | prostate gland |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | DU145 |
| CVCL ID: | CVCL_0105 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Chromatin interaction assay, TF binding assay, Gene expression assay; Chromatin interaction assay; Disease-variant functional analysis |
| High Throughput Method: | Capture 3C-seq, ChIP-seq, RNA-seq, SNP genotyping array; eQTL analysis; GWAS |
| Low Throughput Method: | 3C-qPCR, RT-qPCR; 3C |
About Target Gene
| Target gene : | PPP1R15B |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
15 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02834 | chr1:204518514-204561889 | prostate gland | malignant cell | prostate cancer |
| E_02835 | chr1:204518514-204561889 | prostate gland | malignant cell | prostate cancer |
| E_02836 | chr1:204518514-204561889 | prostate gland | malignant cell | prostate cancer |
| E_02838 | chr1:204518514-204561889 | prostate gland | malignant cell | prostate cancer |
| E_02839 | chr1:204518514-204561889 | prostate gland | malignant cell | prostate cancer |
| E_02840 | chr1:204518514-204561889 | prostate gland | malignant cell | prostate cancer |
| E_02841 | chr1:204518514-204561889 | prostate gland | malignant cell | prostate cancer |
| E_02866 | chr1:204518514-204561889 | prostate gland | prostate epithelial cell | NA |
| E_02867 | chr1:204518514-204561889 | prostate gland | prostate epithelial cell | NA |
| E_02868 | chr1:204518514-204561889 | prostate gland | prostate epithelial cell | NA |
| E_02869 | chr1:204518514-204561889 | prostate gland | prostate epithelial cell | NA |
| E_02883 | chr1:204518514-204561889 | prostate gland | NA | NA |
| E_02884 | chr1:204518514-204561889 | prostate gland | NA | NA |
| E_02885 | chr1:204518514-204561889 | prostate gland | NA | NA |
| E_02886 | chr1:204518514-204561889 | prostate gland | NA | NA |
Expression of Target Genes for the Enhancer