Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02844
Species: Mus musculus
Position : chr8:84109163-84109362
Year: 2015
Title: PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specific Ucp1 gene through interactions with Mediator subunit MED1
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  25644605
MONDO:
Tissue: Embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: Mouse embryonic fibroblasts
CVCL ID: CVCL_0003
Cell Type: mouse embryonic fibroblast
Cell Ontology ID: CL:0000057
Experiment Type: TF binding assay, Functional perturbation assay
High Throughput Method:
Low Throughput Method: ChIP-RT-qPCR, RT-RT-qPCR
About Target Gene
Target gene : Ucp1
About TF
TF name : Prdm16
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Prdm16 PKMTs methylate histone lysines reactome 64
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer