About Enhancer
| Enhancer ID: | E_02857 |
| Species: | Homo sapiens |
| Position : | chr2:85750614-85811383   |
| Year: | 2016 |
| Title: | Chromatin interactions and candidate genes at ten prostate cancer risk loci. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 26979803 |
| MONDO: | MONDO:0008315 |
| Tissue: | prostate gland |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | DU145 |
| CVCL ID: | CVCL_0105 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Chromatin interaction assay, TF binding assay, Gene expression assay; Chromatin interaction assay; Disease-variant functional analysis |
| High Throughput Method: | Capture 3C-seq, ChIP-seq, RNA-seq, SNP genotyping array; eQTL analysis; GWAS |
| Low Throughput Method: | 3C-qPCR, RT-qPCR; 3C |
About Target Gene
| Target gene : | USP39 |
About TF
| TF name : | HOXB13 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| HOXB13 | Regulation of Androgen receptor activity | pid | 54 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
23 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02854 | chr2:85750614-85811383 | prostate gland | malignant cell | prostate cancer |
| E_02855 | chr2:85750614-85811383 | prostate gland | malignant cell | prostate cancer |
| E_02856 | chr2:85750614-85811383 | prostate gland | malignant cell | prostate cancer |
| E_02870 | chr2:85750614-85811383 | prostate gland | prostate epithelial cell | NA |
| E_02871 | chr2:85750614-85811383 | prostate gland | prostate epithelial cell | NA |
| E_02872 | chr2:85750614-85811383 | prostate gland | prostate epithelial cell | NA |
| E_02873 | chr2:85750614-85811383 | prostate gland | prostate epithelial cell | NA |
| E_02893 | chr2:85750614-85811383 | prostate gland | NA | NA |
| E_02894 | chr2:85750614-85811383 | blood | NA | NA |
| E_02895 | chr2:85750614-85811383 | blood | NA | NA |
| E_02896 | chr2:85750614-85811383 | prostate gland | NA | NA |
| E_02897 | chr2:85750614-85811383 | prostate gland | NA | NA |
| E_02898 | chr2:85750614-85811383 | blood | NA | NA |
| E_02899 | chr2:85750614-85811383 | blood | NA | NA |
| E_02900 | chr2:85750614-85811383 | prostate gland | NA | NA |
| E_02901 | chr2:85750614-85811383 | prostate gland | NA | NA |
| E_02902 | chr2:85750614-85811383 | blood | NA | NA |
| E_02903 | chr2:85750614-85811383 | blood | NA | NA |
| E_02904 | chr2:85750614-85811383 | prostate gland | NA | NA |
| E_02905 | chr2:85750614-85811383 | prostate gland | NA | NA |
| E_02906 | chr2:85750614-85811383 | blood | NA | NA |
| E_02907 | chr2:85750614-85811383 | blood | NA | NA |
| E_02908 | chr2:85750614-85811383 | prostate gland | NA | NA |
Expression of Target Genes for the Enhancer