Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02863
Species: Mus musculus
Position : chr3:37283342-37283854
Year: 2010
Title: c-Maf activates the promoter and enhancer of the IL-21 gene, and TGF-beta inhibits c-Maf-induced IL-21 production in CD4+ T cells
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  20042469
MONDO:
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: CD4+ T cell
CVCL ID:
Cell Type: CD4-positive T cell
Cell Ontology ID: CL:0000624
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method:
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, EMSA
About Target Gene
Target gene : Il21
About TF
TF name : C-Maf
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_02861 chr3:37283342-37283854 Lymph node T lymphoma cell T-cell lymphoma
E_02862 chr3:37283342-37283854 Embryonic Kidney embryonic kidney cell --
Expression of Target Genes for the Enhancer