About Enhancer
| Enhancer ID: | E_02864 |
| Species: | Homo sapiens |
| Position : | chr17:26077792-26078792   |
| Year: | 2016 |
| Title: | Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 26751080 |
| Tissue: | lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | A549 |
| CVCL ID: | CVCL_0023 |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; 3C |
About Target Gene
| Target gene : | NOS2 |
About TF
| TF name : | JUND |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| JUND | AP-1 transcription factor network | pid | 71 |
| JUND | ATF-2 transcription factor network | pid | 59 |
| JUND | EGFR1 | netpath | 475 |
| JUND | Inflammation mediated by chemokine and cytokine signaling pathway | panther | 189 |
| JUND | PDGFR-beta signaling pathway | pid | 125 |
| JUND | TGF-beta signaling pathway | panther | 88 |
| JUND | TGF_beta_Receptor | netpath | 220 |
| JUND | Validated transcriptional targets of AP1 family members Fra1 and Fra2 | pid | 37 |
| JUND | MAPK signaling pathway | kegg | 264 |
| JUND | Hs_Apoptosis-related_network_due_to_altered_Notch3_in_ovarian_cancer_WP2864_79278 | wikipathways | 51 |
| JUND | Hs_VEGFA-VEGFR2_Signaling_Pathway_WP3888_90000 | wikipathways | 153 |
| JUND | Hs_Oncostatin_M_Signaling_Pathway_WP2374_73668 | wikipathways | 44 |
| JUND | Hs_EGF-EGFR_Signaling_Pathway_WP437_79266 | wikipathways | 107 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer