About Enhancer
| Enhancer ID: | E_02877 |
| Species: | Homo sapiens |
| Position : | chr20:48400000-49200000   |
| Year: | 2024 |
| Title: | Enhancer-promoter hubs organize transcriptional networks promoting oncogenesis and drug resistance. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast cancer |
| PMID: | 39277592 |
| MONDO: | MONDO:0007254 |
| Tissue: | breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | MDA-MB-157 |
| CVCL ID: | CVCL_0618 |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Chromatin interaction assay; Enhancer activity profiling |
| High Throughput Method: | SMC1 HiChIP; H3K27ac ChIP-seq; RNA-seq |
| Low Throughput Method: | RT-qPCR |
About Target Gene
| Target gene : | CEBPB |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
12 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02876 | chr20:48400000-49200000 | breast | malignant cell | breast cancer |
| E_01098 | chr20:48900221-48901229 | liver | hepatoblast | hepatocellular carcinoma |
| E_01105 | chr20:48900221-48901229 | liver | NA | hepatocellular carcinoma |
| E_01106 | chr20:48900221-48901229 | liver | NA | hepatocellular carcinoma |
| E_01107 | chr20:48900221-48901229 | liver | malignant cell | hepatocellular carcinoma |
| E_01108 | chr20:48900221-48901229 | liver | hepatocyte | hepatocellular carcinoma |
| E_01115 | chr20:48900221-48901229 | liver | NA | hepatocellular carcinoma |
| E_01116 | chr20:48900221-48901229 | liver | NA | hepatocellular carcinoma |
| E_01143 | chr20:48900221-48901229 | uterine cervix | NA | hepatocellular carcinoma |
| E_01145 | chr20:48900221-48901229 | liver | NA | hepatocellular carcinoma |
| E_02830 | chr20:48915257-48915803 | breast | malignant cell | breast cancer |
| E_00953 | chr20:48997377-49019434 | liver | hepatocyte | hepatocellular carcinoma |
Expression of Target Genes for the Enhancer