About Enhancer
| Enhancer ID: | E_02885 |
| Species: | Mus musculus |
| Position : | chr12:53054974-53055029   |
| Year: | 2011 |
| Title: | Suppression of the Pancreatic Duodenal Homeodomain Transcription Factor-1 (Pdx-1) Promoter by Sterol Regulatory Element-binding Protein-1c (SREBP-1c) |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 21652712 |
| MONDO: | |
| Tissue: | Pancreatic islet |
| Tissue Ontology ID: | UBERON:0001264 |
| Cell Source: | INS-1 |
| CVCL ID: | CVCL_0352 |
| Cell Type: | pancreatic beta cell |
| Cell Ontology ID: | CL:0000169 |
| Experiment Type: | TF binding assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, EMSA, ChIP-RT-qPCR |
About Target Gene
| Target gene : | Pdx1 |
About TF
| TF name : | Usf1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Usf1 | Signaling mediated by p38-alpha and p38-beta | pid | 35 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02886 | chr12:53054974-53055029 | Pancreatic islet | pancreatic beta cell | -- |
Expression of Target Genes for the Enhancer