Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02892
Species: Mus musculus
Position : chr3:34752523-34766449
Year: 2019
Title: Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  31422875
MONDO:
Tissue: Embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: Mouse embryonic stem cells (129¡ÁCast F1; v6.5)
CVCL ID: CVCL_2167
Cell Type: mouse embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq, WGBS, ATAC-seq
Low Throughput Method: Transgenic Reporter Assay, CRISPR Knockout, ChIP-qPCR, RT-qPCR, DNA FISH, Immunofluorescence, Confocal Imaging
About Target Gene
Target gene : Sox2
About TF
TF name : Pou5F1; Nanog
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 7 found
Enhancer ID Position Tissue Cell Disease
E_02893 chr3:34752523-34766449 Embryo mouse embryonic stem cell --
E_02608 chr3:34756748-34761748 Embryo mouse embryonic stem cell --
E_03381 chr3:34757100-34758037 Embryo mouse embryonic stem cell --
E_03382 chr3:34757100-34758037 Embryoid body pluripotent stem cell --
E_03383 chr3:34761100-34762000 Embryo mouse embryonic stem cell --
E_03384 chr3:34761100-34762000 Embryoid body pluripotent stem cell --
E_02562 chr3:34765000-34767361 Embryo mouse embryonic stem cell --
Expression of Target Genes for the Enhancer