Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02904
Species: Mus musculus
Position : chr12:113010000-113010100
Year: 2024
Title: Core enhancers of the 3' RR optimize IgH nuclear position and loop conformation for successful oriented class switch recombination
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  39413158
MONDO:
Tissue: Lymph node
Tissue Ontology ID: UBERON:0000029
Cell Source: Primary resting B lymphocytes
CVCL ID:
Cell Type: resting B cell
Cell Ontology ID: CL:0000945
Experiment Type: Functional perturbation assay, Chromatin topology assay
High Throughput Method: ATAC-seq
Low Throughput Method: CRISPR Knockout, CRISPRi, RT-qPCR, FISH
About Target Gene
Target gene : Igh
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_02911 chr12:113010000-113010100 Lymph node plasma cell plasmacytoma
E_02912 chr12:113010000-113010100 Lymph node plasma cell plasmacytoma
Expression of Target Genes for the Enhancer