Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02907
Species: Mus musculus
Position : chr6:122655000-122657500
Year: 2021
Title: Genome editing demonstrates that the -5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  33334884
MONDO:
Tissue: Embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: Mouse embryonic stem cells
CVCL ID:
Cell Type: mouse embryonic stem cell
Cell Ontology ID: CL:0002322
Experiment Type: Functional perturbation assay
High Throughput Method:
Low Throughput Method: CRISPR Knockout, RT-qPCR
About Target Gene
Target gene : Nanog
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 4 found
Enhancer ID Position Tissue Cell Disease
E_02898 chr6:122620000-122660000 Embryo mouse embryonic stem cell --
E_02606 chr6:122652768-122657768 Embryo mouse embryonic stem cell --
E_03335 chr6:122656000-122657000 Embryo mouse embryonic fibroblast --
E_03336 chr6:122656000-122657000 Embryo embryonic stem cell --
Expression of Target Genes for the Enhancer