About Enhancer
| Enhancer ID: | E_02920 |
| Species: | Mus musculus |
| Position : | chr1:136170803-136192554   |
| Year: | 2017 |
| Title: | MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 28575180 |
| MONDO: | |
| Tissue: | Skeletal muscle |
| Tissue Ontology ID: | UBERON:0001134 |
| Cell Source: | C2C12 myoblast cell line |
| CVCL ID: | CVCL_0188 |
| Cell Type: | myoblast |
| Cell Ontology ID: | CL:0000187 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, RNA-seq, 3C-seq |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knockout, ChIP-RT-qPCR, 3C-RT-qPCR, RT-RT-qPCR, Co-IP, DNA pulldown, Western blot |
About Target Gene
| Target gene : | Myog |
About TF
| TF name : | Myod1; Foxo3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
13 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02923 | chr1:136170800-136171203 | Skeletal muscle | myoblast/myotube | -- |
| E_02924 | chr1:136170803-136192554 | Skeletal muscle | myoblast/myotube | -- |
| E_02925 | chr1:136171700-136172103 | Skeletal muscle | myoblast/myotube | -- |
| E_02926 | chr1:136177900-136178345 | Skeletal muscle | myoblast/myotube | -- |
| E_02950 | chr1:136178700-136179145 | Skeletal muscle | myoblast | -- |
| E_03298 | chr1:136179600-136180045 | Skeletal muscle | myoblast | -- |
| E_03013 | chr1:136179654-136180057 | Skeletal muscle | myoblast | -- |
| E_02927 | chr1:136180500-136180903 | Skeletal muscle | myoblast/myotube | -- |
| E_02928 | chr1:136184128-136184880 | Skeletal muscle | myoblast/myotube | -- |
| E_02969 | chr1:136185800-136186245 | Skeletal muscle | myoblast | -- |
| E_03014 | chr1:136185854-136186299 | Skeletal muscle | myoblast | -- |
| E_03305 | chr1:136188400-136188845 | Skeletal muscle | myoblast | -- |
| E_03015 | chr1:136188454-136188857 | Skeletal muscle | myoblast | -- |
Expression of Target Genes for the Enhancer