About Enhancer
| Enhancer ID: | E_02923 |
| Species: | Mus musculus |
| Position : | chr1:136170800-136171203   |
| Year: | 2017 |
| Title: | MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 28575289 |
| MONDO: | |
| Tissue: | Skeletal muscle |
| Tissue Ontology ID: | UBERON:0001134 |
| Cell Source: | Mouse myoblast/myotube cell |
| CVCL ID: | CVCL_0188 |
| Cell Type: | myoblast/myotube |
| Cell Ontology ID: | CL:0000187 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq, 3C-seq |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, CRISPR Knockout, RT-RT-qPCR, 3C-PCR |
About Target Gene
| Target gene : | Myog |
About TF
| TF name : | Myog |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Myog | CDO in myogenesis | reactome | 29 |
| Myog | ID | netpath | 38 |
| Myog | Regulation of nuclear beta catenin signaling and target gene transcription | pid | 80 |
| Myog | Hs_Hypertrophy_Model_WP516_88898 | wikipathways | 17 |
| Myog | Hs_Wnt_Signaling_Pathway_WP428_90292 | wikipathways | 7 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer