About Enhancer
| Enhancer ID: | E_02946 |
| Species: | Mus musculus |
| Position : | chr11:112482190-112483273   |
| Year: | 2024 |
| Title: | Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 38855864 |
| MONDO: | |
| Tissue: | Cartilage |
| Tissue Ontology ID: | UBERON:0002418 |
| Cell Source: | ATDC5 |
| CVCL ID: | CVCL_3894 |
| Cell Type: | chondrogenic cell |
| Cell Ontology ID: | CL:0000138 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knockout, ChIP-RT-qPCR, RT-RT-qPCR, Western blot, Alcian Blue Staining, DNA Pull-Down Assay |
About Target Gene
| Target gene : | Sox9 |
About TF
| TF name : | Pitx1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer