About Enhancer
| Enhancer ID: | E_02953 |
| Species: | Homo sapiens |
| Position : | chr9:123924740-123931280   |
| Year: | 2021 |
| Title: | Genome-wide profiling in colorectal cancer identifies PHF19 and TBC1D16 as oncogenic super enhancers. |
| Genome Build: | hg38 |
| Enhancer Type: | Super-enhancer |
| Condition: | Disease |
| Disease Name: | colorectal cancer |
| PMID: | 34737287 |
| MONDO: | MONDO:0005575 |
| Tissue: | colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | CRC patient tumor tissue |
| Cell Type: | malignant cell |
| Cell Ontology ID: | CL:0001064 |
| Experiment Type: | Super-enhancer identification; Functional validation; Chromatin-state profiling; Disease-variant functional analysis |
| High Throughput Method: | H3K27ac ChIP-seq; H3K4me3 ChIP-seq; RNA-seq; whole-genome sequencing; ChIP-seq |
| Low Throughput Method: | CRISPR interference/functional perturbation; qRT-PCR; tumorigenic functional assays; ChIP |
About Target Gene
| Target gene : | PHF19 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer