About Enhancer
| Enhancer ID: | E_02957 |
| Species: | Mus musculus |
| Position : | chr3:3464735-3477735   |
| Year: | 2015 |
| Title: | CRISPR reveals a distal super-enhancer required for Sox2 expression in mouse embryonic stem cells |
| Genome Build: | mm10 |
| Enhancer Type: | Super-enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 25486255 |
| MONDO: | |
| Tissue: | Embryo |
| Tissue Ontology ID: | UBERON:0000922 |
| Cell Source: | Mouse embryonic stem cells |
| CVCL ID: | |
| Cell Type: | mouse embryonic stem cell |
| Cell Ontology ID: | CL:0002322 |
| Experiment Type: | Functional perturbation assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, RNA-seq, Hi-C |
| Low Throughput Method: | CRISPR Knockout, qRT-PCR, Western blot |
About Target Gene
| Target gene : | Sox2 |
About TF
| TF name : | Pou5F1; Sox2; Nanog |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer