About Enhancer
| Enhancer ID: | E_02967 |
| Species: | Mus musculus |
| Position : | chr3:3103577-3104077   |
| Year: | 2020 |
| Title: | NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 32991700 |
| MONDO: | |
| Tissue: | Skeletal muscle |
| Tissue Ontology ID: | UBERON:0001134 |
| Cell Source: | C2C12 myoblast |
| CVCL ID: | CVCL_0188 |
| Cell Type: | myoblast |
| Cell Ontology ID: | CL:0000187 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | FAIRE-seq, ChIP-seq, RNA-seq |
| Low Throughput Method: | ChIP-RT-qPCR, FAIRE-RT-qPCR, CRISPRi, Luciferase Reporter Assay, RT-RT-qPCR, Oil-Red-O Staining |
About Target Gene
| Target gene : | Pparg |
About TF
| TF name : | Nfia |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Nfia | FOXA1 transcription factor network | pid | 45 |
| Nfia | RNA Polymerase III Abortive And Retractive Initiation | reactome | 41 |
| Nfia | RNA Polymerase III Transcription Termination | reactome | 23 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02968 | chr3:3103577-3104077 | Adipose tissue | preadipocyte | -- |
Expression of Target Genes for the Enhancer