Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02969
Species: Mus musculus
Position : chr1:136185800-136186245
Year: 2017
Title: MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  28575180
MONDO:
Tissue: Skeletal muscle
Tissue Ontology ID: UBERON:0001134
Cell Source: C2C12 myoblast cell line
CVCL ID: CVCL_0188
Cell Type: myoblast
Cell Ontology ID: CL:0000187
Experiment Type: Chromatin interaction assay, TF binding assay
High Throughput Method: ChIP-seq, 3C-seq
Low Throughput Method: 3C-RT-qPCR, ChIP-RT-qPCR, Luciferase Reporter Assay, DNA pulldown, Co-IP
About Target Gene
Target gene : Myog
About TF
TF name : Myod1; Foxo3
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 3 found
Enhancer ID Position Tissue Cell Disease
E_02920 chr1:136170803-136192554 Skeletal muscle myoblast --
E_02924 chr1:136170803-136192554 Skeletal muscle myoblast/myotube --
E_03014 chr1:136185854-136186299 Skeletal muscle myoblast --
Expression of Target Genes for the Enhancer