About Enhancer
| Enhancer ID: | E_02970 |
| Species: | Homo sapiens |
| Position : | chr8:129046628-129096067   |
| Year: | 2018 |
| Title: | Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism. |
| Genome Build: | hg19 |
| Enhancer Type: | Super-enhancer |
| Condition: | Normal |
| PMID: | 29641996 |
| Tissue: | blood / hematopoietic system |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K-562 |
| CVCL ID: | CVCL_0004 |
| Experiment Type: | TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation |
| High Throughput Method: | ChIP-seq; ChIA-PET |
| Low Throughput Method: | CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; 4C; RT-qPCR/qPCR |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_04570 | chr8:129057272-129057795 | blood | malignant cell | NA |
Expression of Target Genes for the Enhancer