About Enhancer
| Enhancer ID: | E_02974 |
| Species: | Mus musculus |
| Position : | chr7:105711382-105713753   |
| Year: | 2020 |
| Title: | A distal enhancer at risk locus 11q135 promotes suppression of colitis by Treg cells |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | colitis |
| PMID: | 32499651 |
| MONDO: | MONDO:0005075 |
| Tissue: | Colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | Primary Treg cells |
| CVCL ID: | |
| Cell Type: | regulatory T cell |
| Cell Ontology ID: | CL:0000815 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay, TF binding assay |
| High Throughput Method: | RNA-seq, ChIP-seq, ATAC-seq |
| Low Throughput Method: | CRISPR Knockout, ChIP-RT-qPCR, qRT-PCR, Flow Cytometry |
About Target Gene
| Target gene : | Lrrc32 |
About TF
| TF name : | Stat5 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer