Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_02978
Species: Mus musculus
Position : chr12:114462800-114464200
Year: 2020
Title: Spt5-mediated enhancer transcription directly couples enhancer activation with physical promoter interaction
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  32251373
MONDO:
Tissue: Spleen
Tissue Ontology ID: UBERON:0002106
Cell Source: Primary mature B cells (activated with LPS + IL-4)
CVCL ID:
Cell Type: activated B cell
Cell Ontology ID: CL:0000945
Experiment Type: Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method: ChIP-seq, GRO-seq, ATAC-seq, 3C-seq
Low Throughput Method: 3C-RT-qPCR, ChIP-RT-qPCR, RT-RT-qPCR, CRISPRa
About Target Gene
Target gene : Ighm,Ighg1
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 3 found
Enhancer ID Position Tissue Cell Disease
E_02077 chr12:114461575-114496377 Spleen mature B cell --
E_02982 chr12:114461575-114496377 Spleen activated B cell --
E_02073 chr12:114462800-114464200 Spleen mature B cell --
Expression of Target Genes for the Enhancer