About Enhancer
| Enhancer ID: | E_02983 |
| Species: | Mus musculus |
| Position : | chr12:85488233-85490498   |
| Year: | 2015 |
| Title: | Stimulus-specific combinatorial functionality of neuronal c-fos enhancers |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 26595767 |
| MONDO: | |
| Tissue: | Brain |
| Tissue Ontology ID: | UBERON:0000955 |
| Cell Source: | Primary mouse cortical neurons |
| CVCL ID: | |
| Cell Type: | cortical neuron |
| Cell Ontology ID: | CL:0000540 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPRi, RT-RT-qPCR |
About Target Gene
| Target gene : | Fos |
About TF
| TF name : | Mef2A |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Mef2A | CDO in myogenesis | reactome | 29 |
| Mef2A | ERK/MAPK targets | reactome | 17 |
| Mef2A | Signaling mediated by p38-alpha and p38-beta | pid | 35 |
| Mef2A | TGF_beta_Receptor | netpath | 220 |
| Mef2A | Hs_p38_MAPK_Signaling_Pathway_WP400_72084 | wikipathways | 28 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02930 | chr12:85486555-85490135 | Cerebral Cortex | cortical neuron | -- |
Expression of Target Genes for the Enhancer