About Enhancer
| Enhancer ID: | E_02994 |
| Species: | Mus musculus |
| Position : | chr8:123406634-123407310   |
| Year: | 2016 |
| Title: | Long-range enhancers modulate Foxf1 transcription in blood vessels of pulmonary vascular network |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | pulmonary vascular disease |
| PMID: | 27166834 |
| MONDO: | MONDO:0005022 |
| Tissue: | Lung |
| Tissue Ontology ID: | UBERON:0002048 |
| Cell Source: | Embryonic lung cells |
| CVCL ID: | |
| Cell Type: | embryonic lung cell |
| Cell Ontology ID: | CL:0000000 |
| Experiment Type: | Chromatin interaction assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | 3C-seq, Luciferase Reporter Assay, RT-RT-qPCR |
About Target Gene
| Target gene : | Foxf1 |
About TF
| TF name : | Gli1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Gli1 | Ci/Gli processing signaling ( Hedgehog signaling pathway ) | inoh | 17 |
| Gli1 | Degradation of GLI1 by the proteasome | reactome | 59 |
| Gli1 | FAS signaling pathway | panther | 37 |
| Gli1 | GLI proteins bind promoters of Hh responsive genes to promote transcription | reactome | 7 |
| Gli1 | Hedgehog 'off' state | reactome | 43 |
| Gli1 | Hedgehog 'on' state | reactome | 72 |
| Gli1 | Hedgehog | netpath | 39 |
| Gli1 | Hedgehog signaling events mediated by Gli proteins | pid | 49 |
| Gli1 | Hedgehog signaling pathway | panther | 19 |
| Gli1 | Signaling without Hh ( Hedgehog signaling pathway ) | inoh | 7 |
| Gli1 | Hedgehog signaling pathway | kegg | 53 |
| Gli1 | Pathways in cancer | kegg | 321 |
| Gli1 | Basal cell carcinoma | kegg | 51 |
| Gli1 | Hs_Dopaminergic_Neurogenesis_WP2855_87239 | wikipathways | 19 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer