About Enhancer
| Enhancer ID: | E_02998 |
| Species: | Mus musculus |
| Position : | chr18:37380000-37385000   |
| Year: | 2020 |
| Title: | Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 32293525 |
| MONDO: | |
| Tissue: | Cerebral cortex |
| Tissue Ontology ID: | UBERON:0000956 |
| Cell Source: | Primary cortical neurons |
| CVCL ID: | CVCL_0470 |
| Cell Type: | cortical neuron |
| Cell Ontology ID: | CL:0000540 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq, 5C, QHR-4C, Single-cell RNA-seq |
| Low Throughput Method: | CRISPR Knockout, dCas9 Blocking, RT-RT-qPCR |
About Target Gene
| Target gene : | Pcdhb |
About TF
| TF name : | Ctcf |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Ctcf | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| Ctcf | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_02999 | chr18:37380000-37385000 | Brain | neuroblastoma cell | -- |
Expression of Target Genes for the Enhancer