Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03003
Species: Mus musculus
Position : chr7:6650000-6650600
Year: 2013
Title: Identification of an Evolutionarily Conserved Cis-Regulatory Element Controlling the Peg3 Imprinted Domain
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  24040411
MONDO:
Tissue: Brain
Tissue Ontology ID: UBERON:0000955
Cell Source: Neuro-2a cells
CVCL ID: CVCL_0470
Cell Type: neuroblastoma cell
Cell Ontology ID: CL:0000031
Experiment Type: Enhancer activity assay
High Throughput Method: ChIP-seq
Low Throughput Method: 3C assay, Luciferase reporter assay, RT-RT-qPCR
About Target Gene
Target gene : Peg3
About TF
TF name : Yy1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Yy1 Activation of anterior HOX genes in hindbrain development during early embryogenesis reactome 120
Yy1 DNA Damage Recognition in GG-NER reactome 38
Yy1 E2F transcription factor network pid 77
Yy1 mTOR signaling pathway pid 66
Yy1 Notch-mediated HES/HEY network pid 48
Yy1 Notch netpath 76
Yy1 Notch signaling pathway pid 58
Yy1 p53 pathway pid 59
Yy1 Signaling events mediated by HDAC Class I pid 89
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer