Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03011
Species: Mus musculus
Position : chr11:5202000-5255000
Year: 2017
Title: STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Disease
Disease Name: immune dysregulation
PMID:  29078395
MONDO: MONDO:0005317
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: CD4+ T cells
CVCL ID:
Cell Type: CD4-positive T cell
Cell Ontology ID: CL:0000624
Experiment Type: Chromatin interaction assay, Functional perturbation assay
High Throughput Method: ChIA-PET, RNA-seq
Low Throughput Method: CRISPR knockout, Luciferase reporter assay, RT-RT-qPCR
About Target Gene
Target gene : Il2Ra
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_03026 chr11:5202000-5255000 Blood CD4-positive T cell immune dysregulation
Expression of Target Genes for the Enhancer