Comprehensive information about experimentally validated enhancers
| Enhancer ID: | E_03011 |
| Species: | Mus musculus |
| Position : | chr11:5202000-5255000 |
| Year: | 2017 |
| Title: | STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | immune dysregulation |
| PMID: | 29078395 |
| MONDO: | MONDO:0005317 |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | CD4+ T cells |
| CVCL ID: | |
| Cell Type: | CD4-positive T cell |
| Cell Ontology ID: | CL:0000624 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIA-PET, RNA-seq |
| Low Throughput Method: | CRISPR knockout, Luciferase reporter assay, RT-RT-qPCR |
| Target gene : | Il2Ra |
| TF name : |
| Regulatory State : | Active |
| GeneName | Pathway Name | Source | Gene Number |
|---|
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03026 | chr11:5202000-5255000 | Blood | CD4-positive T cell | immune dysregulation |