About Enhancer
| Enhancer ID: | E_03017 |
| Species: | Mus musculus |
| Position : | chr15:4422074-4423282   |
| Year: | 2019 |
| Title: | LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis |
| Genome Build: | mm10 |
| Enhancer Type: | Super-enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 30638865 |
| MONDO: | |
| Tissue: | Liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | Primary mouse hepatocytes |
| CVCL ID: | |
| Cell Type: | hepatocyte |
| Cell Ontology ID: | CL:0000182 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | Ppara |
About TF
| TF name : | Nr5A2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Nr5A2 | Nuclear Receptor transcription pathway | reactome | 51 |
| Nr5A2 | Regulation of gene expression in early pancreatic precursor cells | reactome | 8 |
| Nr5A2 | Maturity onset diabetes of the young | kegg | 25 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer