About Enhancer
| Enhancer ID: | E_03053 |
| Species: | Mus musculus |
| Position : | chr16:24176502-24213494   |
| Year: | 2025 |
| Title: | CFP1 promotes germinal center affinity maturation and restrains memory B cell differentiation through H3K4me3 modulation |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 40866336 |
| MONDO: | |
| Tissue: | Spleen |
| Tissue Ontology ID: | UBERON:0002106 |
| Cell Source: | Germinal center B cells |
| CVCL ID: | |
| Cell Type: | germinal center B cell |
| Cell Ontology ID: | CL:0000945 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | 3C-seq, RNA-seq, ChIP-seq |
| Low Throughput Method: | 3C-RT-qPCR, qRT-PCR, Western blot |
About Target Gene
| Target gene : | Bcl6 |
About TF
| TF name : | Mef2B |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Mef2B | CDO in myogenesis | reactome | 29 |
| Mef2B | p38 MAPK pathway | panther | 31 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer