About Enhancer
| Enhancer ID: | E_03056 |
| Species: | Homo sapiens |
| Position : | chr12:6444399-6447744   |
| Year: | 2025 |
| Title: | Evidence for enhancer activity in intron 1 of TNFRSF1A using CRISPR/Cas9 in human induced pluripotent stem cell-derived macrophages. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 41057395 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | iPSC-derived macrophages |
| Cell Type: | macrophage |
| Cell Ontology ID: | CL:0000235 |
| Experiment Type: | Enhancer activity assay; Endogenous enhancer perturbation; Chromatin-state profiling; Disease-variant functional analysis |
| High Throughput Method: | ATAC-seq, ChIP-seq; RNA-seq; ATAC-seq; ChIP-seq; GWAS |
| Low Throughput Method: | CRISPR Knockout, Luciferase Reporter Assay; CRISPR-Cas9 endogenous deletion/editing; ChIP |
About Target Gene
| Target gene : | TNFRSF1A |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer