Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03062
Species: Homo sapiens
Position : chr8:128747000-128748000
Year: 2020
Title: Transcription imparts architecture, function and logic to enhancer units.
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
PMID:  32958950
Tissue: blood
Tissue Ontology ID: UBERON:0000178
Cell Source: K-562
CVCL ID: CVCL_0004
Cell Type: malignant cell
Cell Ontology ID: CL:0001064
Experiment Type: Enhancer activity assay, Functional perturbation assay; Enhancer activity assay; Endogenous enhancer perturbation
High Throughput Method: ChIP-seq, ATAC-seq, RNA-seq; MPRA
Low Throughput Method: Luciferase Reporter Assay, CRISPR Knockout, RT-RT-qPCR; CRISPR-Cas9 endogenous deletion/editing; Reporter assay
About Target Gene
Target gene : MYC
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 3 found
Enhancer ID Position Tissue Cell Disease
E_03876 chr8:126650000-129950000 colon malignant cell NA
E_03680 chr8:128740000-128750000 blood malignant cell myeloid malignancy
E_03681 chr8:128740000-128750000 blood malignant cell myeloid malignancy
Expression of Target Genes for the Enhancer