About Enhancer
| Enhancer ID: | E_03062 |
| Species: | Mus musculus |
| Position : | chr8:87424785-87425735   |
| Year: | 2015 |
| Title: | The DEK Oncoprotein Is a Critical Component of the EKLF/KLF1 enhancer in erythroid cells |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 26303528 |
| MONDO: | |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Mouse erythroid progenitor cells |
| CVCL ID: | |
| Cell Type: | erythroid progenitor cell |
| Cell Ontology ID: | CL:0000038 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | RNA-seq |
| Low Throughput Method: | ChIP-RT-qPCR, CRISPR Knockout, shRNA knockdown, RT-RT-qPCR, Western blot, EMSA, Transgenic Reporter Assay |
About Target Gene
| Target gene : | Klf1 |
About TF
| TF name : | Dek |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Dek | B-WICH complex positively regulates rRNA expression | reactome | 89 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer