About Enhancer
| Enhancer ID: | E_03067 |
| Species: | Homo sapiens |
| Position : | chr2:29880537-29880842   |
| Year: | 2017 |
| Title: | PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | alveolar rhabdomyosarcoma |
| PMID: | 28446439 |
| MONDO: | MONDO:0009994 |
| Tissue: | skeletal muscle tissue |
| Tissue Ontology ID: | UBERON:0001134 |
| Cell Source: | RH 4 |
| CVCL ID: | CVCL_B6EX |
| Cell Type: | rhabdomyosarcoma cell |
| Experiment Type: | Enhancer activity assay, Super-enhancer profiling |
| High Throughput Method: | ChIP-seq; RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay; CRISPR Knockout |
About Target Gene
| Target gene : | ALK |
About TF
| TF name : | PAX3::FOXO1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg19)
No overlapping enhancers found in hg19 at this locus.
Expression of Target Genes for the Enhancer