Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03074
Species: Mus musculus
Position : chr17:33930235-37702617
Year: 2023
Title: Histone demethylase KDM5D upregulation drives sex differences in colon cancer
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Disease
Disease Name: colorectal cancer
PMID:  37344599
MONDO: MONDO:0005176
Tissue: Colon
Tissue Ontology ID: UBERON:0001155
Cell Source: iKAP colorectal cancer cells
CVCL ID:
Cell Type: colorectal cancer cell
Cell Ontology ID: CL:0000066
Experiment Type: Chromatin interaction, Functional perturbation
High Throughput Method: HiChIP, ChIP-seq, RNA-seq
Low Throughput Method: RT-RT-qPCR, Western blot, Flow cytometry, T cell killing assay
About Target Gene
Target gene : Tap1
About TF
TF name :
About Regulatory State
Regulatory State : Silenced
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 15 found
Enhancer ID Position Tissue Cell Disease
E_02481 chr17:34048994-34049208 Lens lens epithelial cell --
E_02482 chr17:34048994-34049208 Lens lens fiber cell --
E_02483 chr17:34049209-34050661 Lens lens epithelial cell --
E_02484 chr17:34049209-34050661 Lens lens fiber cell --
E_02485 chr17:34060350-34061356 Lens lens epithelial cell --
E_02486 chr17:34060350-34061356 Lens lens fiber cell --
E_02430 chr17:34210000-34250000 Bone marrow monocyte-dendritic cell progenitor --
E_02439 chr17:34520000-34525000 Lung pulmonary artery endothelial cell --
E_02458 chr17:34540000-34542000 Embryo fibroblast --
E_02557 chr17:35500000-35501700 Embryo mouse embryonic fibroblast --
E_02080 chr17:35600000-35630000 Embryo mouse embryonic stem cell --
E_02464 chr17:35602100-35602600 Embryo mouse embryonic stem cell --
E_02866 chr17:35605300-35605800 Embryo mouse embryonic stem cell --
E_03021 chr17:35643073-35645472 Embryo mouse embryonic fibroblast --
E_03361 chr17:35643473-35645472 Embryo embryonic stem cell --
Expression of Target Genes for the Enhancer