About Enhancer
| Enhancer ID: | E_03090 |
| Species: | Mus musculus |
| Position : | chr5:145320091-145322975   |
| Year: | 2008 |
| Title: | Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 19141476 |
| MONDO: | |
| Tissue: | Pancreas |
| Tissue Ontology ID: | UBERON:0001264 |
| Cell Source: | Pancreatic primordium |
| CVCL ID: | |
| Cell Type: | pancreatic epithelial cell |
| Cell Ontology ID: | CL:0002078 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | Pdx1 |
About TF
| TF name : | Foxa1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Foxa1 | AndrogenReceptor | netpath | 167 |
| Foxa1 | Direct p53 effectors | pid | 141 |
| Foxa1 | FOXA1 transcription factor network | pid | 45 |
| Foxa1 | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| Foxa1 | Hs_Endoderm_Differentiation_WP2853_88152 | wikipathways | 62 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer