About Enhancer
| Enhancer ID: | E_03091 |
| Species: | Mus musculus |
| Position : | chr9:121540000-121545000   |
| Year: | 2024 |
| Title: | Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | proliferative vitreoretinopathy |
| PMID: | 39183203 |
| MONDO: | MONDO:0006007 |
| Tissue: | Retina |
| Tissue Ontology ID: | UBERON:0000966 |
| Cell Source: | Primary retinal pigment epithelium (RPE) cells |
| CVCL ID: | |
| Cell Type: | retinal pigment epithelial cell |
| Cell Ontology ID: | CL:0002586 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ATAC-seq, ChIP-seq, RNA-seq |
| Low Throughput Method: | RT-RT-qPCR, Western blot, Immunofluorescence |
About Target Gene
| Target gene : | Tnfrsf11A (Rank) |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer