About Enhancer
| Enhancer ID: | E_03104 |
| Species: | Homo sapiens |
| Position : | chr13:20993543-20994585   |
| Year: | 2022 |
| Title: | 3D Chromatin Organization Involving MEIS1 Factor in the cis-Regulatory Landscape of GJB2. |
| Genome Build: | hg19 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 35805969 |
| Tissue: | respiratory airway |
| Tissue Ontology ID: | UBERON:0001005 |
| Cell Source: | Small airway epithelial cells (SAEC) |
| Cell Type: | respiratory epithelial cell |
| Experiment Type: | Enhancer activity assay; TF binding assay; Chromatin interaction assay; Functional perturbation assay |
| High Throughput Method: | 4C-seq; 4C |
| Low Throughput Method: | CRISPRi; MEIS1 ChIP-PCR; RT-qPCR; Endpoint RT-PCR |
About Target Gene
| Target gene : | GJB2 |
About TF
| TF name : | MEIS1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| MEIS1 | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
Enhancer Associated Network
Overlapping Enhancers (hg19)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_03060 | chr13:20993543-20994585 | kidney | embryonic kidney cell | NA |
Expression of Target Genes for the Enhancer