Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_03118
Species: Mus musculus
Position : chr11:112634637-112637797
Year: 2017
Title: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  28045957
MONDO:
Tissue: Testis
Tissue Ontology ID: UBERON:0000473
Cell Source: Sertoli cells
CVCL ID:
Cell Type: Sertoli cell
Cell Ontology ID: CL:0000216
Experiment Type: Enhancer activity assay, Functional perturbation assay, TF binding assay
High Throughput Method: RNA-seq
Low Throughput Method: CRISPR knockout, RT-RT-qPCR, Immunofluorescence, ChIP-RT-qPCR
About Target Gene
Target gene : Sox9
About TF
TF name : Sry
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Sry AndrogenReceptor netpath 167
Sry Deactivation of the beta-catenin transactivating complex reactome 42
Sry Regulation of Androgen receptor activity pid 54
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_03119 chr11:112635500-112636792 Testis Sertoli cell --
Expression of Target Genes for the Enhancer