About Enhancer
| Enhancer ID: | E_03135 |
| Species: | Mus musculus |
| Position : | chr6:126984000-126986000   |
| Year: | 2018 |
| Title: | A Novel Distal Enhancer Mediates Inflammation-, PTH-, and Early Onset Murine Kidney Disease-Induced Expression of the Mouse Fgf23 Gene |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | chronic kidney disease |
| PMID: | 29527594 |
| MONDO: | MONDO:0005102 |
| Tissue: | Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | Osteocytes |
| CVCL ID: | |
| Cell Type: | osteocyte |
| Cell Ontology ID: | CL:0000064 |
| Experiment Type: | Functional genomics assay, Epigenomic profiling assay, Transcriptional regulation assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | ChIP-RT-qPCR, qRT-PCR, Genotyping PCR, Sanger Sequencing |
About Target Gene
| Target gene : | Fgf23 |
About TF
| TF name : | Ctcf |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Ctcf | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| Ctcf | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
No overlapping enhancers found in mm10 at this locus.
Expression of Target Genes for the Enhancer