About Enhancer
| Enhancer ID: | E_03138 |
| Species: | Mus musculus |
| Position : | chr11:44203545-44203644   |
| Year: | 2011 |
| Title: | A distal enhancer in Il12b is the target of transcriptional repression by the STAT3 Pathway and Requires the Basic Leucine Zipper (B-ZIP) Protein NFIL3 |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 21566115 |
| MONDO: | |
| Tissue: | Bone Marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | Bone marrow-derived macrophages |
| CVCL ID: | |
| Cell Type: | macrophage |
| Cell Ontology ID: | CL:0000235 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, qRT-PCR, Western blot, EMSA, Knockout Mouse Model, Mass Spectrometry |
About Target Gene
| Target gene : | Il12B |
About TF
| TF name : | Nfil3 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
4 found
Expression of Target Genes for the Enhancer